GLT-1 overexpression attenuates bladder nociception and local/cross-organ sensitization of bladder nociception
نویسندگان
چکیده
منابع مشابه
GLT-1 overexpression attenuates bladder nociception and local/cross-organ sensitization of bladder nociception.
Glutamatergic pathways mediate transmission of pain. Strategies to reduce glutamatergic neurotransmission may have beneficial effects to mitigate nociception. Recent work revealed that overexpression of the astrocytic glutamate transporter (GLT-1) by transgenic or pharmacologic approaches produced a diminished visceral nociceptive response to colonic distension. The purpose of this study was to...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Renal Physiology
سال: 2011
ISSN: 1931-857X,1522-1466
DOI: 10.1152/ajprenal.00009.2011